Development and validation of a driving simulator for evaluating the residual effects of drugs on driving performance – sensitivity analysis using zopiclone as a positive control: Study Protocol Clinical Trial (SPIRIT Compliant)

INTRODUCTION: Drugs acting on the central nervous system (CNS), especially hypnotics, can impair driving. The US Food and Drug Administration started requiring pharmaceutical companies to evaluate the residual influence of CNS agents on driving performance to review their recommended doses. Although...

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Publicat a:Medicine (Baltimore)
Autors principals: Iwata, Mari, Iwamoto, Kunihiro, Kambe, Daiji, Tachibana, Naoki, Ando, Masahiko, Ozaki, Norio
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2020
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3700
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220102/
https://ncbi.nlm.nih.gov/pubmed/32195934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000019395
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