Development and validation of a driving simulator for evaluating the residual effects of drugs on driving performance – sensitivity analysis using zopiclone as a positive control: Study Protocol Clinical Trial (SPIRIT Compliant)

INTRODUCTION: Drugs acting on the central nervous system (CNS), especially hypnotics, can impair driving. The US Food and Drug Administration started requiring pharmaceutical companies to evaluate the residual influence of CNS agents on driving performance to review their recommended doses. Although...

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Publicado en:Medicine (Baltimore)
Autores principales: Iwata, Mari, Iwamoto, Kunihiro, Kambe, Daiji, Tachibana, Naoki, Ando, Masahiko, Ozaki, Norio
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Health 2020
Materias:
3700
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220102/
https://ncbi.nlm.nih.gov/pubmed/32195934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000019395
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