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Busulfan Pharmacokinetics and Precision Dosing: Are Patients with Fanconi Anemia Different?

It is well known that pharmacokinetics (PK) guided busulfan (BU) dosing increases engraftment rates and lowers hepatotoxicity in patients undergoing hematopoietic cell transplantation (HCT). However, there are no published PK data in patients with Fanconi anemia (FA) who are known to have baseline D...

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Библиографические подробности
Опубликовано в: :Biol Blood Marrow Transplant
Главные авторы: Mehta, Parinda A., Emoto, Chie, Fukuda, Tsuyoshi, Seyboth, Brian, Teusink-Cross, Ashley, Davies, Stella M., Wilhelm, Jamie, Fuller, Kirsten, Vinks, Alexander A., Boulad, Farid
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219959/
https://ncbi.nlm.nih.gov/pubmed/31326610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2019.07.014
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