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Transcutaneous immunization with a nontypeable Haemophilus influenzae dual adhesin-directed immunogen induces durable and boostable immunity

Otitis media (OM) is a very common pediatric disease and nontypeable Haemophilus influenzae (NTHI) is the predominant causative agent. We’ve developed a chimeric immunogen, chimV4, that simultaneously targets two NTHI adhesins, OMP P5 and the type IV pilus. Transcutaneous immunization (TCI) via band...

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Bibliografski detalji
Izdano u:Vaccine
Glavni autori: Novotny, Laura A., Bakaletz, Lauren O.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219548/
https://ncbi.nlm.nih.gov/pubmed/32001071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.01.052
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