Transcutaneous immunization as preventative and therapeutic regimens to protect against experimental otitis media due to nontypeable Haemophilus influenzae

We have developed three nontypeable Haemophilus influenzae (NTHI) adhesin-derived immunogens that are significantly efficacious against experimental otitis media (OM) due to NTHI when delivered parenterally. We now expanded our preventative immunization strategies to include transcutaneous immunizat...

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Main Authors: Novotny, L A, Clements, J D, Bakaletz, L O
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118858/
https://ncbi.nlm.nih.gov/pubmed/21326197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.6
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