Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2

SARS-CoV-2-caused COVID-19 cases are growing globally, calling for developing effective therapeutics to control the current pandemic. SARS-CoV-2 and SARS-CoV recognize angiotensin-converting enzyme 2 (ACE2) receptor via the receptor-binding domain (RBD). Here, we identified six SARS-CoV RBD-specific...

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Bibliographic Details
Published in:Antiviral Res
Main Authors: Tai, Wanbo, Zhang, Xiujuan, He, Yuxian, Jiang, Shibo, Du, Lanying
Format: Artigo
Language:Inglês
Published: Elsevier B.V. 2020
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219369/
https://ncbi.nlm.nih.gov/pubmed/32405117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104820
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