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Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the capacity to suppress adaptive immune responses during cancer. It remains elusive how MDSCs differ from their normal myeloid counterparts, which limits our ability to specifically detect and therapeutically target MDSCs...

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Publicat a:Sci Immunol
Autors principals: Alshetaiwi, Hamad, Pervolarakis, Nicholas, McIntyre, Laura Lynn, Ma, Dennis, Nguyen, Quy, Rath, Jan Akara, Nee, Kevin, Hernandez, Grace, Evans, Katrina, Torosian, Leona, Silva, Anushka, Walsh, Craig, Kessenbrock, Kai
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219211/
https://ncbi.nlm.nih.gov/pubmed/32086381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aay6017
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