Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the capacity to suppress adaptive immune responses during cancer. It remains elusive how MDSCs differ from their normal myeloid counterparts, which limits our ability to specifically detect and therapeutically target MDSCs...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Alshetaiwi, Hamad, Pervolarakis, Nicholas, McIntyre, Laura Lynn, Ma, Dennis, Nguyen, Quy, Rath, Jan Akara, Nee, Kevin, Hernandez, Grace, Evans, Katrina, Torosian, Leona, Silva, Anushka, Walsh, Craig, Kessenbrock, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219211/
https://ncbi.nlm.nih.gov/pubmed/32086381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aay6017
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