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Development of zirconium-89 PET for in vivo imaging of alpha-klotho

Alpha-klotho is a single-pass membrane protein primarily expressed by the kidneys. Klotho deficiency in chronic kidney disease contributes to an accelerated aging phenotype. We report here development of [(89)Zr]DFO-anti-klotho positron emission tomography (PET) imaging as a novel non-invasive metho...

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Detalhes bibliográficos
Publicado no:Am J Nucl Med Mol Imaging
Main Authors: Lau, Wei Ling, Liang, Christopher, Liu, Han, Singh, Karanveer, Mukherjee, Jogeshwar
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218695/
https://ncbi.nlm.nih.gov/pubmed/32419978
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