A luminal unfolding microneedle injector for oral delivery of macromolecules

Insulin and other injectable biologic drugs have transformed the treatment of patients suffering from diabetes. Patients and healthcare providers, however, prefer the oral route of administration, yet macromolecule drugs are not readily absorbed into the bloodstream through the gastrointestinal trac...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Abramson, Alex, Caffarel-Salvador, Ester, Soares, Vance, Minahan, Daniel, Tian, Ryan Yu, Lu, Xiaoya, Dellal, David, Gao, Yuan, Kim, Soyoung, Wainer, Jacob, Collins, Joy, Tamang, Siddartha, Hayward, Alison, Yoshitake, Tadayuki, Lee, Hsiang-Chieh, Fujimoto, James, Fels, Johannes, Frederiksen, Morten Revsgaard, Rahbek, Ulrik, Roxhed, Niclas, Langer, Robert, Traverso, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218658/
https://ncbi.nlm.nih.gov/pubmed/31591601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-019-0598-9
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