HE4 overexpression decreases pancreatic cancer Capan-1 cell sensitivity to paclitaxel via cell cycle regulation

BACKGROUND: Paclitaxel is a first-line chemotherapy drug for pancreatic, ovarian, endometrial cancers and other malignancies. However, its efficacy is often compromised by decreased cell sensitivity or the development of resistance. Human epididymis protein 4 (HE4) is highly expressed in gynecologic...

Full description

Saved in:
Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Guo, Fengbiao, Li, Jinping, Qi, Yaozhi, Hou, Jianqing, Chen, Haibin, Jiang, Shi-Wen
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218645/
https://ncbi.nlm.nih.gov/pubmed/32435154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01248-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items