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HE4 overexpression decreases pancreatic cancer Capan-1 cell sensitivity to paclitaxel via cell cycle regulation

BACKGROUND: Paclitaxel is a first-line chemotherapy drug for pancreatic, ovarian, endometrial cancers and other malignancies. However, its efficacy is often compromised by decreased cell sensitivity or the development of resistance. Human epididymis protein 4 (HE4) is highly expressed in gynecologic...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Guo, Fengbiao, Li, Jinping, Qi, Yaozhi, Hou, Jianqing, Chen, Haibin, Jiang, Shi-Wen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218645/
https://ncbi.nlm.nih.gov/pubmed/32435154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01248-1
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