CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model

BACKGROUND: Anti-tumor effects of radiation therapy (RT) largely depend on host immune function. Adenosine with its strong immunosuppressive properties is an important immune checkpoint molecule. METHOD: We examined how intra-tumoral adenosine levels modify anti-tumor effects of RT in a murine model...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Tsukui, Hidenori, Horie, Hisanaga, Koinuma, Koji, Ohzawa, Hideyuki, Sakuma, Yasunaru, Hosoya, Yoshinori, Yamaguchi, Hironori, Yoshimura, Kotaro, Lefor, Alan Kawarai, Sata, Naohiro, Kitayama, Joji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218548/
https://ncbi.nlm.nih.gov/pubmed/32397971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06893-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados