Asiatic acid attenuates hypertrophic and fibrotic differentiation of articular chondrocytes via AMPK/PI3K/AKT signaling pathway

BACKGROUND: Osteoarthritis (OA), the most common joint disorder, is characterized by a progressive degradation of articular cartilage. Increasing evidence suggests that OA is closely associated with cartilage pathologies including chondrocyte hypertrophy and fibrosis. METHODS: In this study, we show...

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Pubblicato in:Arthritis Res Ther
Autori principali: Liu, Na, Fu, Dejie, Yang, Junjun, Liu, Pingju, Song, Xiongbo, Wang, Xin, Li, Rui, Fu, Zhenlan, Chen, Jiajia, Gong, Xiaoyuan, Chen, Cheng, Yang, Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218496/
https://ncbi.nlm.nih.gov/pubmed/32398124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02193-0
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