Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection

Ocular herpes simplex virus 1 (HSV-1) infection leads to an immunopathogenic disease called herpes stromal keratitis (HSK), in which CD4(+) T cell-driven inflammation contributes to irreversible damage to the cornea. Herpesvirus entry mediator (HVEM) is an immune modulator that activates stimulatory...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Park, Seo J., Riccio, Rachel E., Kopp, Sarah J., Ifergan, Igal, Miller, Stephen D., Longnecker, Richard
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218284/
https://ncbi.nlm.nih.gov/pubmed/32398314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00790-20
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