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Disease Module Identification Based on Representation Learning of Complex Networks Integrated From GWAS, eQTL Summaries, and Human Interactome

The study of disease-relevant gene modules is one of the main methods to discover disease pathway and potential drug targets. Recent studies have found that most disease proteins tend to form many separate connected components and scatter across the protein-protein interaction network. However, most...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Wang, Tao, Peng, Qidi, Liu, Bo, Liu, Yongzhuang, Wang, Yadong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218106/
https://ncbi.nlm.nih.gov/pubmed/32435638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00418
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