Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity through Non-Canonical p53 and Akt Signaling

Group 1 metabotropic glutamate receptors (Gp1 mGluRs), including mGluR1 and mGluR5, are critical regulators for neuronal and synaptic plasticity. Dysregulated Gp1 mGluR signaling is observed with various neurologic disorders, including Alzheimer’s disease, Parkinson’s disease, epilepsy, and autism s...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Liu, Dai-Chi, Soriano, Stephanie, Yook, Yeeun, Lizarazo, Simon, Eagleman, Daphne E., Tsai, Nien-Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Article: New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218008/
https://ncbi.nlm.nih.gov/pubmed/32161037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0438-19.2020
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