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EGFR Signaling Causes Morphine Tolerance and Mechanical Sensitization in Rats

The safety and efficacy of opioids are compromised as analgesic tolerance develops. Opioids are also ineffective against neuropathic pain. Recent reports have suggested that inhibitors of the epidermal growth factor receptor (EGFR), a receptor tyrosine kinase (RTK), may have analgesic effects in can...

詳細記述

保存先:
書誌詳細
出版年:eNeuro
主要な著者: Puig, Stephanie, Donica, Courtney L., Gutstein, Howard B.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218007/
https://ncbi.nlm.nih.gov/pubmed/32111605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0460-18.2020
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