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Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior
Newly born neurons express high levels of TUBA1A α-tubulin to assemble microtubules for neurite extension and to provide tracks for intracellular transport. In the adult brain, Tuba1a expression decreases dramatically. A mouse that harbors a loss-of-function mutation in the gene encoding TUBA1A (Tub...
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| Publicado no: | eNeuro |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7218002/ https://ncbi.nlm.nih.gov/pubmed/32184299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0045-20.2020 |
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