PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

Despite well-known peripheral immune activation in posttraumatic stress disorder (PTSD), there are no studies of brain immunologic regulation in individuals with PTSD. [(11)C]PBR28 Positron Emission Tomography brain imaging of the 18-kDa translocator protein (TSPO), a microglial biomarker, was condu...

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Publicado en:Nat Commun
Main Authors: Bhatt, Shivani, Hillmer, Ansel T., Girgenti, Matthew J., Rusowicz, Aleksandra, Kapinos, Michael, Nabulsi, Nabeel, Huang, Yiyun, Matuskey, David, Angarita, Gustavo A., Esterlis, Irina, Davis, Margaret T., Southwick, Steven M., Friedman, Matthew J., Duman, Ronald S., Carson, Richard E., Krystal, John H., Pietrzak, Robert H., Cosgrove, Kelly P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217830/
https://ncbi.nlm.nih.gov/pubmed/32398677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15930-5
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