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Focused ultrasound induced-blood–brain barrier opening in mouse brain receiving radiosurgery dose of radiation enhances local delivery of systemic therapy

OBJECTIVE: Investigate the temporal effects of focused ultrasound (FUS)-induced blood–brain barrier (BBB) opening in post-radiotherapy mouse brains. METHODS AND MATERIALS: C57B6 mice without tumors were used to simulate the scenario after gross total resection (GTR) of brain tumor. Radiation dose of...

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Vydáno v:Br J Radiol
Hlavní autoři: Wang, Shutao, Wu, Cheng-Chia, Zhang, Hairong, Karakatsani, Maria Eleni, Wang, Yi-Fang, Han, Yang, Chaudhary, Kunal R, Wuu, Cheng-Shie, Konofagou, Elisa, Cheng, Simon K
Médium: Artigo
Jazyk:Inglês
Vydáno: The British Institute of Radiology. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217580/
https://ncbi.nlm.nih.gov/pubmed/31999201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20190214
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