Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells

Type III interferons (IFN-lambdas(λ)) are important cytokines that inhibit viruses and modulate immune responses by acting through a unique IFN-λR1/IL-10RB heterodimeric receptor. Until now, the primary antiviral function of IFN-λs has been proposed to be at anatomical barrier sites. Here, we examin...

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Publicat a:PLoS Pathog
Autors principals: Santer, Deanna M., Minty, Gillian E. S., Golec, Dominic P., Lu, Julia, May, Julia, Namdar, Afshin, Shah, Juhi, Elahi, Shokrollah, Proud, David, Joyce, Michael, Tyrrell, D. Lorne, Houghton, Michael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217487/
https://ncbi.nlm.nih.gov/pubmed/32353085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008515
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