Overexpression of HIF-1α protects PC12 cells against OGD/R-evoked injury by reducing miR-134 expression

Nowadays, searching for new therapeutic targets for cerebral stroke treatment are still in urgent need. Our study explored the influences and mechanisms of HIF-1α on OGD/R-evoked injury. OGD/R treatment was conducted on PC12 cells to simulate ischemic injury. CCK-8, flow cytometry and qRT-PCR were c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Cycle
Egile Nagusiak: Zhang, Hongliang, Liu, Xianming, Yang, Fengyu, Cheng, Dekui, Liu, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217352/
https://ncbi.nlm.nih.gov/pubmed/32266863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1743903
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