Dexmedetomidine protects PC12 cells from oxidative damage through regulation of miR-199a/HIF-1α

Background Although dexmedetomidine (Dex) has a significant neuroprotective effect in various nerve-damage models, the exact mechanism of which Dex protects cells from oxidative damage is not fully clear. This article recommended the protective effect of Dex on oxidative damage in PC12 cells.Methods...

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Hlavní autoři: Ling Wu, Yalin Xi, Qinglong Kong
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2020-01-01
Edice:Artificial Cells, Nanomedicine, and Biotechnology
Témata:
PC12 cells
dexmedetomidine
oxidative damage
miR-199a
HIF-1α
On-line přístup:https://www.tandfonline.com/doi/10.1080/21691401.2020.1716780
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