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Inhibition of Aurora Kinase A by Alisertib Reduces Cell Proliferation and Induces Apoptosis and Autophagy in HuH-6 Human Hepatoblastoma Cells

PURPOSE: Aurora kinase A (AURKA), which belongs to the serine/threonine protein kinase family, has been identified as a key driver of the genesis and progression of diverse tumors. The aim of this study was to determine the clinical significance of AURKA in patients with hepatoblastoma (HB) and the...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Tan, Jingyi, Xu, Wenfeng, Lei, Lei, Liu, Hui, Wang, Hong, Cao, Xian, Xu, Man
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217307/
https://ncbi.nlm.nih.gov/pubmed/32440158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S228656
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