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Sphingosine kinases protect murine embryonic stem cells from sphingosine‐induced cell cycle arrest
Sphingosine‐1‐phosphate (S1P) is a bioactive lipid molecule regulating organogenesis, angiogenesis, cell proliferation, and apoptosis. S1P is generated by sphingosine kinases (SPHK1 and SPHK2) through the phosphorylation of ceramide‐derived sphingosine. Phenotypes caused by manipulating S1P metaboli...
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| Publié dans: | Stem Cells |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley & Sons, Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7217063/ https://ncbi.nlm.nih.gov/pubmed/31916656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3145 |
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