Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics

Dysregulated expression and activity of cathepsin S (CTSS), a lysosomal protease and a member of the cysteine cathepsin protease family, is linked to the pathogenesis of multiple diseases, including a number of conditions affecting the lungs. Extracellular CTSS has potent elastase activity and by pr...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Brown, Ryan, Nath, Sridesh, Lora, Alnardo, Samaha, Ghassan, Elgamal, Ziyad, Kaiser, Ryan, Taggart, Clifford, Weldon, Sinéad, Geraghty, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216426/
https://ncbi.nlm.nih.gov/pubmed/32398133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01381-5
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