Protein Phosphatase 2A Reduces Cigarette Smoke–induced Cathepsin S and Loss of Lung Function

Rationale: CTSS (cathepsin S) is a cysteine protease that is observed at higher concentrations in BAL fluid and plasma of subjects with chronic obstructive pulmonary disease (COPD). Objectives: To investigate whether CTSS is involved in the pathogenesis of cigarette smoke–induced COPD and determine...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Doherty, Declan F., Nath, Sridesh, Poon, Justin, Foronjy, Robert F., Ohlmeyer, Michael, Dabo, Abdoulaye J., Salathe, Matthias, Birrell, Mark, Belvisi, Maria, Baumlin, Nathalie, Kim, Michael D., Weldon, Sinéad, Taggart, Clifford, Geraghty, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603057/
https://ncbi.nlm.nih.gov/pubmed/30641028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201808-1518OC
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