Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells

BACKGROUND: The thymus is a highly specialized organ of the immune system where T cell precursors develop and differentiate into self-tolerant CD4+ or CD8+ T cells. No studies to date have investigated how the human transcriptome profiles differ, between T cells still residing in the thymus and T ce...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Helgeland, Hanna, Gabrielsen, Ingvild, Akselsen, Helle, Sundaram, Arvind Y. M., Flåm, Siri Tennebø, Lie, Benedicte Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216358/
https://ncbi.nlm.nih.gov/pubmed/32393182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6755-1
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