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O(6)-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability

The genome of living cells is continuously exposed to endogenous and exogenous attacks, and this is particularly amplified at high temperatures. Alkylating agents cause DNA damage, leading to mutations and cell death; for this reason, they also play a central role in chemotherapy treatments. A class...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Mattossovich, Rosanna, Merlo, Rosa, Miggiano, Riccardo, Valenti, Anna, Perugino, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216122/
https://ncbi.nlm.nih.gov/pubmed/32326075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082878
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