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O(6)-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability

The genome of living cells is continuously exposed to endogenous and exogenous attacks, and this is particularly amplified at high temperatures. Alkylating agents cause DNA damage, leading to mutations and cell death; for this reason, they also play a central role in chemotherapy treatments. A class...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Mattossovich, Rosanna, Merlo, Rosa, Miggiano, Riccardo, Valenti, Anna, Perugino, Giuseppe
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216122/
https://ncbi.nlm.nih.gov/pubmed/32326075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082878
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