Enhanced Cellular Uptake and Photodynamic Effect with Amphiphilic Fluorinated Porphyrins: The Role of Sulfoester Groups and the Nature of Reactive Oxygen Species

A class of amphiphilic photosensitizers for photodynamic therapy (PDT) was developed. Sulfonate esters of modified porphyrins bearing—F substituents in the ortho positions of the phenyl rings have adequate properties for PDT, including absorption in the red, increased cellular uptake, favorable intr...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pucelik, Barbara, Sułek, Adam, Drozd, Agnieszka, Stochel, Grażyna, Pereira, Mariette M., Pinto, Sara M. A., Arnaut, Luis G., Dąbrowski, Janusz M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216003/
https://ncbi.nlm.nih.gov/pubmed/32316355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082786
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