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Photodynamic Inactivation of Bacteria with Porphyrin Derivatives: Effect of Charge, Lipophilicity, ROS Generation, and Cellular Uptake on Their Biological Activity In Vitro

Resistance of microorganisms to antibiotics has led to research on various therapeutic strategies with different mechanisms of action, including photodynamic inactivation (PDI). In this work, we evaluated a cationic, neutral, and anionic meso-tetraphenylporphyrin derivative’s ability to inactivate t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Sułek, Adam, Pucelik, Barbara, Kobielusz, Marcin, Barzowska, Agata, Dąbrowski, Janusz M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698881/
https://ncbi.nlm.nih.gov/pubmed/33218103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228716
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