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Glycyrrhizin Inhibits PEDV Infection and Proinflammatory Cytokine Secretion via the HMGB1/TLR4-MAPK p38 Pathway

Our previous study showed that glycyrrhizin (GLY) inhibited porcine epidemic diarrhea virus (PEDV) infection, but the mechanisms of GLY anti-PEDV action remain unclear. In this study, we focused on the anti-PEDV and anti-proinflammatory cytokine secretion mechanisms of GLY. We found that PEDV infect...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Gao, Ruyi, Zhang, Yongshuai, Kang, Yuhui, Xu, Weiyin, Jiang, Luyao, Guo, Tingting, Huan, Changchao
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215578/
https://ncbi.nlm.nih.gov/pubmed/32340172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082961
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