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Promiscuous Roles of Autophagy and Proteasome in Neurodegenerative Proteinopathies

Alterations in autophagy and the ubiquitin proteasome system (UPS) are commonly implicated in protein aggregation and toxicity which manifest in a number of neurological disorders. In fact, both UPS and autophagy alterations are bound to the aggregation, spreading and toxicity of the so-called prion...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Limanaqi, Fiona, Biagioni, Francesca, Gambardella, Stefano, Familiari, Pietro, Frati, Alessandro, Fornai, Francesco
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215558/
https://ncbi.nlm.nih.gov/pubmed/32344772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21083028
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