Tetramethylpyrazine Induces Apoptosis and Inhibits Proliferation of Hypertrophic Scar-Derived Fibroblasts via Inhibiting the Phosphorylation of AKT

Hypertrophic scar (HS) is a serious fibrotic skin disease and often considered as a kind of benign skin tumor. Tetramethylpyrazine (TMP), the main chemical composition of the traditional Chinese medicine Chuanxiong Rhizoma, has shown significant clinical benefits in the treatment of fibrosis disease...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Wu, Xue, Wang, Zheng, Wu, Gaofeng, Xu, Xiaofan, Zhang, Jian, Li, Yan, Zhang, Hong, Guo, Shuzhen
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214921/
https://ncbi.nlm.nih.gov/pubmed/32431617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00602
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