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Aged Tendon Stem/Progenitor Cells Are Less Competent to Form 3D Tendon Organoids Due to Cell Autonomous and Matrix Production Deficits

Tendons are dense connective tissues, which are critical for the integrity and function of our musculoskeletal system. During tendon aging and degeneration, tendon stem/progenitor cells (TSPCs) experience profound phenotypic changes with declined cellular functions that can be linked to the known in...

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Bibliografiske detaljer
Udgivet i:Front Bioeng Biotechnol
Main Authors: Yan, Zexing, Yin, Heyong, Brochhausen, Christoph, Pfeifer, Christian G., Alt, Volker, Docheva, Denitsa
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214752/
https://ncbi.nlm.nih.gov/pubmed/32432103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00406
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