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Aged Tendon Stem/Progenitor Cells Are Less Competent to Form 3D Tendon Organoids Due to Cell Autonomous and Matrix Production Deficits

Tendons are dense connective tissues, which are critical for the integrity and function of our musculoskeletal system. During tendon aging and degeneration, tendon stem/progenitor cells (TSPCs) experience profound phenotypic changes with declined cellular functions that can be linked to the known in...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Yan, Zexing, Yin, Heyong, Brochhausen, Christoph, Pfeifer, Christian G., Alt, Volker, Docheva, Denitsa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214752/
https://ncbi.nlm.nih.gov/pubmed/32432103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00406
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