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T-Bet Expression Mediated by the mTOR Pathway Influences CD4(+) T Cell Count in Mice With Lethal Candida Sepsis

The sustained high morbidity and mortality of Candida sepsis are mainly caused by compromise of host immunity. Clinically, it is often manifested as a significant decrease in CD4(+) T cell count, although the mechanism is unclear. We established a lethal mice Candida sepsis model and used Murine Sep...

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Podrobná bibliografie
Vydáno v:Front Microbiol
Hlavní autoři: Bai, Guangxu, Wang, Hao, Han, Wen, Cui, Na
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214724/
https://ncbi.nlm.nih.gov/pubmed/32431684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00835
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