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T-cell-specific mTOR deletion in mice ameliorated CD4(+) T-cell survival in lethal sepsis induced by severe invasive candidiasis
The mammalian target of rapamycin (mTOR) pathway can mediate T-cell survival; however, the role of this pathway in T-cell survival during fungal sepsis is unclear. Here, we investigated the role of the mTOR pathway in CD4(+) T-cell survival in a mouse model of rapidly progressive lethal sepsis induc...
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| Pubblicato in: | Virulence |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844314/ https://ncbi.nlm.nih.gov/pubmed/31668132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2019.1685151 |
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