Thrombopoietin enhances hematopoietic stem and progenitor cell homing by impeding matrix metalloproteinase 9 expression

We reported a novel function of recombinant human thrombopoietin (TPO) in increasing hematopoietic stem and progenitor cell (HSPC) homing to the bone marrow (BM). Single doses of TPO treatment to the recipients immediately after BM transplantation showed significantly improved homing of HSPCs to the...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Liu, Yiming, Ding, Li, Zhang, Bowen, Deng, Ziliang, Han, Yi, Wang, Sihan, Yang, Shu, Fan, Zeng, Zhang, Jing, Yan, Hongmin, Han, Dongmei, He, Lijuan, Yue, Wen, Wang, Hengxiang, Li, Yanhua, Pei, Xuetao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Human Clinical Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214666/
https://ncbi.nlm.nih.gov/pubmed/32125099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0220
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