Thrombopoietin enhances hematopoietic stem and progenitor cell homing by impeding matrix metalloproteinase 9 expression

We reported a novel function of recombinant human thrombopoietin (TPO) in increasing hematopoietic stem and progenitor cell (HSPC) homing to the bone marrow (BM). Single doses of TPO treatment to the recipients immediately after BM transplantation showed significantly improved homing of HSPCs to the...

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Détails bibliographiques
Publié dans:Stem Cells Transl Med
Auteurs principaux: Liu, Yiming, Ding, Li, Zhang, Bowen, Deng, Ziliang, Han, Yi, Wang, Sihan, Yang, Shu, Fan, Zeng, Zhang, Jing, Yan, Hongmin, Han, Dongmei, He, Lijuan, Yue, Wen, Wang, Hengxiang, Li, Yanhua, Pei, Xuetao
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2020
Sujets:
Human Clinical Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214666/
https://ncbi.nlm.nih.gov/pubmed/32125099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0220
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