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Omiganan Enhances Imiquimod‐Induced Inflammatory Responses in Skin of Healthy Volunteers

Omiganan (OMN; a synthetic cationic peptide) and imiquimod (IMQ; a TLR7 agonist) have synergistic effects on interferon responses in vitro. The objective of this study was to translate this to a human model for proof‐of‐concept, and to explore the potential of OMN add‐on treatment for viral skin dis...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Niemeyer‐van der Kolk, Tessa, Assil, Salma, Buters, Thomas P., Rijsbergen, Melanie, Klaassen, Erica S., Feiss, Gary, Florencia, Edwin, Prens, Errol P., Burggraaf, Jacobus, van Doorn, Martijn B.A., Rissmann, Robert, Moerland, Matthijs
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214655/
https://ncbi.nlm.nih.gov/pubmed/32043302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12741
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