Comprehensive, Multimodal Characterization of an Imiquimod‐Induced Human Skin Inflammation Model for Drug Development

Imiquimod (IMQ) is often used as a topical challenge agent to provoke local skin inflammation. The objective of this study was to develop and refine a rapid, temporary, and reversible human skin inflammation model with IMQ for application in clinical drug development. A randomized, vehicle‐controlle...

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Опубликовано в: :Clin Transl Sci
Главные авторы: van der Kolk, Tessa, Assil, Salma, Rijneveld, Rianne, Klaassen, Erica S., Feiss, Gary, Florencia, Edwin, Prens, Errol P., Burggraaf, Jacobus, Moerland, Matthijs, Rissmann, Robert, van Doorn, Martijn B.A.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226121/
https://ncbi.nlm.nih.gov/pubmed/29768709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12563
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