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TIGIT Blockade: A Multipronged Approach to Target the HIV Reservoir

During chronic human immunodeficiency virus type 1 (HIV-1) infection, upregulation of inhibitory molecules contributes to effector cell dysfunction and exhaustion. This, in combination with the ability of HIV-1 to reside dormant in cellular reservoirs and escape immune recognition, makes the pathway...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Holder, Kayla A., Grant, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214612/
https://ncbi.nlm.nih.gov/pubmed/32432050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00175
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