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The Glutamate System as a Crucial Regulator of CNS Toxicity and Survival of HIV Reservoirs

Glutamate (Glu) is the most abundant excitatory neurotransmitter in the central nervous system (CNS). HIV-1 and viral proteins compromise glutamate synaptic transmission, resulting in poor cell-to-cell signaling and bystander toxicity. In this study, we identified that myeloid HIV-1-brain reservoirs...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Gorska, Anna Maria, Eugenin, Eliseo A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326772/
https://ncbi.nlm.nih.gov/pubmed/32670889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00261
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