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Benzoxazines as new human topoisomerase I inhibitors and potential poisons

BACKGROUND: The numbers of topoisomerase I targeted drugs on the market are very limited although they are used clinically for treatment of solid tumors. Hence, studies about finding new chemical structures which specifically target topoisomerase I are still remarkable. OBJECTIVES: In this present s...

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Bibliografiske detaljer
Udgivet i:Daru
Main Authors: Foto, Egemen, Özen, Çigdem, Zilifdar, Fatma, Tekiner-Gülbaş, Betül, Yıldız, İlkay, Akı-Yalçın, Esin, Diril, Nuran, Yalçın, İsmail
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214584/
https://ncbi.nlm.nih.gov/pubmed/31832989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-019-00315-x
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