Multiplex precise base editing in cynomolgus monkeys

Common polygenic diseases result from compounded risk contributed by multiple genetic variants, meaning that simultaneous correction or introduction of single nucleotide variants is required for disease modeling and gene therapy. Here, we show precise, efficient, and simultaneous multiplex base edit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Zhang, Wenhui, Aida, Tomomi, del Rosario, Ricardo C. H., Wilde, Jonathan J., Ding, Chenhui, Zhang, Xiaohui, Baloch, Zulqurain, Huang, Yan, Tang, Yu, Li, Duanduan, Lu, Hongyu, Zhou, Yang, Jiang, Minqing, Xu, Dongdong, Fang, Zhihao, Zheng, Zhanhong, Huang, Qunshan, Feng, Guoping, Yang, Shihua
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214463/
https://ncbi.nlm.nih.gov/pubmed/32393762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16173-0
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