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Translating evidence into practice: eligibility criteria fail to eliminate clinically significant differences between real-world and study populations

Randomized controlled trials (RCTs) are regarded as the most reputable source of evidence. In some studies, factors beyond the intervention itself may contribute to the measured effect, an occurrence known as heterogeneity of treatment effect (HTE). If the RCT population differs from the real-world...

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Detalhes bibliográficos
Publicado no:NPJ Digit Med
Main Authors: Averitt, Amelia J., Weng, Chunhua, Ryan, Patrick, Perotte, Adler
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214444/
https://ncbi.nlm.nih.gov/pubmed/32411828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41746-020-0277-8
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