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Translating evidence into practice: eligibility criteria fail to eliminate clinically significant differences between real-world and study populations

Randomized controlled trials (RCTs) are regarded as the most reputable source of evidence. In some studies, factors beyond the intervention itself may contribute to the measured effect, an occurrence known as heterogeneity of treatment effect (HTE). If the RCT population differs from the real-world...

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Publicat a:NPJ Digit Med
Autors principals: Averitt, Amelia J., Weng, Chunhua, Ryan, Patrick, Perotte, Adler
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214444/
https://ncbi.nlm.nih.gov/pubmed/32411828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41746-020-0277-8
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