Metformin suppresses proliferation and invasion of drug‐resistant breast cancer cells by activation of the Hippo pathway

Drug resistance limits the clinical efficacy of breast cancer therapies, and overexpression or activation of Yes‐associated protein (YAP) is common in drug‐resistant cancer cells. Thus, inhibition of YAP may reduce resistance to anti‐cancer drugs. Metformin (MET), a first‐line diabetes medication th...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Liu, Jie, Li, Juan, Chen, He, Wang, Ruiqi, Li, Pingping, Miao, Yi, Liu, Peijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214175/
https://ncbi.nlm.nih.gov/pubmed/32281270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15241
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