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Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway

Discs Large Homolog 5 (DLG5) plays an important role in the maintenance of epithelial cell polarity. Recent research showed that DLG5 is decreased in Yes-associated protein (YAP)-overexpressing cells. However, the exact relationship between DLG5 and YAP is not clear. In this study, we showed that lo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Jie, Li, Juan, Li, Pingping, Wang, Yaochun, Liang, Zheyong, Jiang, Yina, Li, Jing, Feng, Chen, Wang, Ruiqi, Chen, He, Zhou, Can, Zhang, Jianmin, Yang, Jin, Liu, Peijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294562/
https://ncbi.nlm.nih.gov/pubmed/28169360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42125
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